Arteriosclerosis: the first 10 years.

Tadalafil attenuates graft arteriosclerosis of aortic transplant in a rat model

Objective(s): Tadalafil can restore endothelial function and treat atherosclerosis. However, the effect of tadalafil on transplant arteriosclerosis remains unclear. In this study, we explore the effects of tadalafil on allograft vasculopathy. Materials and Methods: Male Brow-Norway rats supplied aorta grafts for Male Lewis rats. All recipients were divided into 3 groups: saline as placebo (con...

Effect of olive leaf, mulberry leaf and fenugreek seed extract on plasma cholesterols and fatty streaks at aorta wall on hypercholestrolemic rabbit

Introduction: dyslipidemia is one of the most important risk factors that cause arteriosclerosis in the coronary artery. The aim of this study was to investigate olive and mulberry leaf , fenugreek seed– dyethylether extract on plasma lipid levels and arteriosclerosis plaques. Materials & Methods: 45 white male rabbits divided into nine groups of five at 22 ±1C.The first and second group were ...

Prevention of Heart Disease by Controlling Risk Factors

For a long period of time some different hypothesis have been published about arteriosclerosis but none of them has discovered the pathogenesis and effective treat­ment of this entity. By elemination of risk factors it is not clear that the disease process stops or reverses. Pre­ventiona and treatment of risk factors should start before manifestation of arteriosclerosis sympthoms. The result of...

Spontaneous Arteriosclerosis in Rabbits

Decreased level of serum carnitine might lead to arteriosclerosis progression via the accumulation of advanced glycation end products in maintenance hemodialysis patients

Background: Carnitine is reported to improve insulin resistance and reduce oxidative stress. Hyperglycemia and increased oxidative stress are well known to promote the production of advanced glycation end products (AGEs) that can lead to arteriosclerosis in patients with maintenance hemodialysis (HD). In the present study, we aimed to determine whether decreased level of serum carnitine acceler...